G9a mediates Sharp-1–dependent inhibition of skeletal muscle differentiation
نویسندگان
چکیده
منابع مشابه
G9a mediates Sharp-1–dependent inhibition of skeletal muscle differentiation
Sharp-1, a basic helix-loop-helix transcription factor, is a potent repressor of skeletal muscle differentiation and is dysregulated in muscle pathologies. However, the mechanisms by which it inhibits myogenesis are not fully understood. Here we show that G9a, a lysine methyltransferase, is involved in Sharp-1-mediated inhibition of muscle differentiation. We demonstrate that G9a directly inter...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2012
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.e12-04-0311